Entries by Sharon Jacob MD

ACD to cigarettes – Balsam of Peru and Chocolate fragrance

“Additives to Cigarette Tobacco… Cocoa Products Cocoa and cocoa products are used as a main flavor additive in the Philip Morris cigarette brands (Philip Morris USA, Richmond, VA)-Virginia Slims, Marlboro, and Parliament (Table 2).[10]Cocoa is from the Sterculiaceae family (also called the Malvaceae family). Cocoa beans are processed into cocoa powder to make chocolate.[11] Individuals who […]

New article came out on isothiazolinone cross reactivity (mice)

Br J Dermatol. 2016 Jun 25. doi: 10.1111/bjd.14825. [Epub ahead of print] Cross-reactivity between methylisothiazolinone, octylisothiazolinone and benzisothiazolinone using a modified local lymph node assay. Schwensen JF1, Menné Bonefeld C2, Zachariae C3, Agerbeck C2, H Petersen T2, Geisler C2, E Bollmann U4, Bester K4, D Johansen J1. Author information Abstract BACKGROUND: In the light of the exceptionally high rates of contact allergy to the preservative methylisothiazolinone (MI), information about […]

Free Article – American Contact Alternatives Group (ACAG) – Hair Products

The American Contact Alternatives Group evaluates allergen trends and alternative products – Check out the free article here: Part 2 of a 4-part series Hair Products: Trends and Alternatives: Data from the American Contact Alternatives Group. Scheman A, Jacob S, Katta R, Nedorost S, Warshaw E, Zirwas M, Bhinder M J Clin Aesthet Dermatol. 2011 Jul;4(7):42-6. […]

Free Article – American Contact Alternatives Group (ACAG) – Facial Cosmetics

The American Contact Alternatives Group evaluates allergen trends and alternative products – Check out the free article here: Part 1 of a 4-part series: Facial Cosmetics: Trends and Alternatives: Data from the American Contact Alternatives Group. Scheman A, Jacob S, Katta R, Nedorost S, Warshaw E, Zirwas M, Cha C. “To provide updated data on […]

Late Delayed Reactions – 13%

“Patch test readings are usually performed on day 2 (48 hours) and day 4 (96 hours). However, reports in the literature identify delayed allergy to metals, corticosteroids, antibiotics, some preservatives, acrylic and methacrylic monomers and p-phenylenediamine.”   This article discusses 203 patients that were patch tested to the British Society for Cutaneous Allergy standard series and […]

On patch testing and the T.R.U.E. test

What is Patch Testing?  Patch testing is a method for diagnosing delayed type hypersensitivity.  Chemicals (haptens) are applied on the skin with wells adhered to an adhesive strip.  The wells may be hand-loaded (‘comprehensive’) patch testing or may be preloaded in gels (‘patch test kit’, e.g.: T.R.U.E. test).   They are then left in contact […]

Formaldehyde exposure

On Formaldehyde exposure …formaldehyde is an important irritant and allergen.  Irritants disrupt the skin and permit increased absorption of allergens…  “Formaldehyde is the simplest of the aldehydes (HCHO). It is a gas at room temperature. It is obtainable in crystalline form or as a liquid. … There are two major sources of formaldehyde: direct commercial manufacture and […]