Entries by Sharon Jacob MD

Pre-Emptive Avoidance Strategy Update

Brankov N1, Jacob SE2. Pre-Emptive Avoidance Strategy (P.E.A.S) 2016: Update on Pediatric Contact Dermatitis Allergens. Expert Rev Clin Immunol. 2016 Nov 18. [Epub ahead of print] The New Pre-Emptive Avoidance Strategy (P.E.A.S.) Update is published. New PEAS: 1. Fragrance Mix 1 and 2/Balsam of Peru (and derivatives) 2. Neomycin/Bacitracin 3. Wool wax/Amerchol/lanolin 4. Formaldehyde/bronopol/Q15 5. MCI and […]

Nickel reactions within minutes to hours – confirmed by prick testing.

This is a most important work by Dr. Doug Powell’s group, which highlights non-delayed type hypersensitivity immune activation to nickel (nickel immediate reactions).  In our practice we see patients with atopic dermatitis that flare in response to nickel exposure.  This is an area in need of further investigation.  Article will be in print this month! Saluja […]

European Society CD Meeting – highlights

This week marked the Manchester UK, European Society of Contact Dermatitis Meeting 14-17 September 2016…  There was so much top notch research presented  by international researchers. Poster P016: Octylisothiazolinone is a relevant nonoccupational contact allergen in leather goods and may show cross-reactivity to methyisothiazolinone.   J. Leysen et al. Poster P020: Airborne bullous allergic contact […]

Free Article- Cosmetic Contact Allergens by An Goossens!

This is a FREE open access article that discusses common and not so common allergens in cosmetics.  Section  3.2.2. discusses preservatives: “Shifts in frequency of positive patch-test reactions have occurred over the years [6 ], but more recently methylisothiazolinone (MI), in particular … weaker sensitizer… less efficient … hence larger use concentrations … severe skin lesions and atypical clinical […]

The conifer – balsam of Peru connection discussed – Systemic Contact Dermatitis

Systemic contact dermatitis is a systemic response to an allergen in a previously sensitized individual.  This article presents a case of a woman with ‘dyshidrotic hand eczema’ who developed blisters after eating chocolate.  She also had fever and an elevated immune cell count.  This patient benefited from a BOP-reduced diet. …”many of the components of […]

SNAS – 700 patients evaluated

This is important work from the Italians… 700 patients evaluated with the systemic nickel allergy syndrome having both skin and GI symptoms.  Patch testing helped confirm the diagnosis. Tammaro A1, Romano I1, De Marco G1, Parisella FR2, Pigliacelli F1, D’Arino A1, Persechino F3, Gaspari AA2, Persechino S1. Effects of TIO NICKEL in patients with ACD […]

Octylisothiazolinone! Anti-fungal on Leather!

This is an important article this week, because OIT isn’t just an occupational allergen and it can cross-react with MI. Contact Dermatitis. 2016 Aug 19. doi: 10.1111/cod.12670. [Epub ahead of print] Octylisothiazolinone, an additional cause of allergic contact dermatitis caused by leather: case series and potential implications for the study of cross-reactivity with methylisothiazolinone. Abstract BACKGROUND: Octylisothiazolinone […]