NEW- ALLERGEN MATTERS – ATOPICS as greater risk for… BOP… Lanolin

/in , /by

Cocamidopropyl betaine, Amerchol L-101 {lanolin} and many of the Fragrances are only available for testing with comprehensive patch testing.  Propylene glycol and MI also ones that can be frequently missed, because they are not specifically tested.  P.E.A.S – pre-emptive [allergen] avoidance strategy highlights this top allergens and Simple and Free highlights products devoid of them…

“Lubbes S1, Rustemeyer T2, Sillevis Smitt JH1, Schuttelaar MA3, Middelkamp-Hup MA1.    Contact sensitization in Dutch children and adolescents with and without atopic dermatitis - a retrospective analysis.     Contact Dermatitis. 2016 Nov 11. doi: 10.1111/cod.12711.
BACKGROUND:
Allergic contact dermatitis is known to occur in children with and without atopic dermatitis, but more data are needed on contact sensitization profiles in these two groups.
OBJECTIVES:
To identify frequent allergens in children with and without atopic dermatitis suspected of having allergic contact dermatitis.

METHODS:
A retrospective analysis of children aged 0-17 years patch tested between 1996 and 2013 was performed.

RESULTS:
Of all 1012 children tested because of suspected contact dermatitis, 46% developed one or more positive reactions, the proportions for children with (n = 526) and without (n = 395) atopic dermatitis being 48% and 47%, respectively. Children with atopic dermatitis reacted more often to lanolin alcohols (30% pet., p = 0.030), Amerchol L-101 (p = 0.030), and fragrances [fragrance mix I (p = 0.048) and Myroxylon pereirae {BOP} (p = 0.005)].   Allergens outside the European baseline series that frequently gave positive reactions in these groups included cocamidopropyl betaine and Amerchol L-101. Reactivity to these allergens was significantly more frequently found in atopic dermatitis children.

CONCLUSION:
Sensitization prevalences in children with and without atopic dermatitis were similar, but children with atopic dermatitis reacted significantly more often to lanolin alcohols and fragrances. Testing with additional series besides the European baseline series may be necessary, as reactions to, for example, cocamidopropyl betaine and Amerchol L-101 may otherwise be missed.”

https://www.ncbi.nlm.nih.gov/pubmed/27861990