New data regarding Wet Wipe Allergens from the North American Contact Dermatitis Group!
New data regarding Wet Wipe Allergens from the North American Contact Dermatitis Group!
There have been several case reports of wipe-associated contact dermatitis, however, the aim of this study was to determine the prevalence of wipe-associated contact dermatitis in a larger population This study looked at 9037 patients patch tested from 2011-2014 to determine the prevalence of wet wipes as a source of contact allergy.
What did they find?
79(0.9%) had a positive patch test to an allergen associated with a wet-wipe source. Anal/genital dermatitis was 15 times more likely in those with a wet-wipe allergy!
What were the most associated allergens
Preservatives and fragrance:
- Methylisothiazolinone (59.0%)
- Methychloroisothiazolinone (MCI)/MI (35.6%)
- Bronopol (2-bromo-2-nitropropane-1,3-diol) (27.4%)
- Iodopropynyl butylcarbamate (12.3%)
- Fragrance (combined) represented (12.3%)
What was their conclusion?
Although uncommon (0.9%), Wet wipes are an important source of contact allergy to consider with anal/genital dermatitis. Preservatives such as Isothiazolinones are an especially important source to consider!
Warshaw EM, Aschenbeck KA, Zug KA, Belsito DV, Zirwas MJ, Fowler JF Jr, Taylor
JS, Sasseville D, Fransway AF, DeLeo VA, Marks JG Jr, Pratt MD, Maibach HI,
Mathias CG, DeKoven JG. Wet Wipe Allergens: Retrospective Analysis From the North
American Contact Dermatitis Group 2011-2014. Dermatitis. 2017
