Para-Pheneylenediamine (PPD)
Allergic contact dermatitis is a T-cell dependent, delayed-type (Type IV) hypersensitivity reaction that has a high impact both in terms of patient morbidity and economics. This type of hypersensitivity reaction is primarily instigated by small lipophilic chemicals (haptens) with a molecular weight less than 500 Daltons. These chemical allergens trigger a complex immunologic cascade in the skin, which leads to the clinical picture of allergic contact dermatitis. Click on the links below to find out more information about Para-pheneylenediamine Allergic Contact Dermatitis.
Para-Pheneylenediamine: Review Video
“PPD is a dark dye used in almost all permanent hair dyes and in some semi-permanent hair coloring. You may find PPD in some temporary henna tattoos. Very rarely it can be found in photographic developers, textile dyes and printing inks.”
Para-Phenylenediamine: Review Article
“Para-phenylenediamine, a widely used culprit behind millions of reported and unreported cases of ACD, is an oxidative substance that was initially formulated for use in dye at the end of the 19th century.”
