SNAS – 700 patients evaluated

This is important work from the Italians… 700 patients evaluated with the systemic nickel allergy syndrome having both skin and GI symptoms.  Patch testing helped confirm the diagnosis.

Tammaro A1, Romano I1, De Marco G1, Parisella FR2, Pigliacelli F1, D’Arino A1, Persechino F3, Gaspari AA2, Persechino S1.

Effects of TIO NICKEL in patients with ACD and SNAS: experience on 700 patients in Italy.

J Eur Acad Dermatol Venereol. 2016 Aug 12. doi: 10.1111/jdv.13916. [Epub ahead of print]
Abstract
The nickel is causes of allergic contact dermatitis (ACD) and of “systemic nickel allergy syndrome” (SNAS). From 2009 to 2015 a very large number of patients with allergies, presented to our Department of Dermatology and Allergology at Sant’Andrea Hospital in Rome; 700 of these showed an allergic reaction to nickel with a double clinical manifestation, skin and gastrointestinal symptoms, between 25 and 60 years old. Regarding the skin manifestation, the diagnosis was confirmed by Patch Test SIDAPA standard series. The results were positive for nickel sulphate with +2 to +3, using the ICDRG scoring system, and also to others allergens (Table 1). This article is protected by copyright. All rights reserved.

 

http://onlinelibrary.wiley.com/doi/10.1111/jdv.13916/pdf